We defined “size-normalized sensitivity” (SnS) by multiplying UV 254 sensitivities ( D 37 values) by the genome size, and SnS values were relatively constant for viruses with similar genetic composition. We calculated D 37 values (fluence producing on average one lethal hit per virion and reducing viable virus to 37%) from all available data. We reviewed published reports on 254-nm UV inactivation and tabulated the sensitivities of a wide variety of viruses, including those with double-stranded DNA, single-stranded DNA, double-stranded RNA, or single-stranded RNA genomes. The goal of this study was to estimate inactivation of viruses by solar exposure. UV radiation from the sun is the primary germicide in the environment.
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